The days of the human race on the planet are numbered. A terrible plague has emptied the cities that are now overgrown with the jungle. Everything mankind has ever achieved – economy, law, culture – is gone. The rest of those who have avoided the infection are roaming the wasteland fighting each other for resources. This war is very hard to wage alone. Two complete strangers – an experienced ranger called Joel and a teenage girl named Ellie – are brought together by fate and join forces in an effort to survive in this new cruel world.