The Binding of Isaac Afterbirth

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Game description:

You play for Isaac, a son of the woman who hears voices in her head. She believes that the Lord is talking to her and he is what he says: “If you want to prove that your faith in Me is worthy, then prove it and kill your own son. This will show that you have nothing more valuable in your life than Me, your Lord.” Being ready to fulfill the order, the mother realizes that Isaac is gone! You will play for him in this bizarre adventure, shooting your enemies and facing the worst nightmares imaginable. Get super-powers, reveal creepy mysteries, and find your way to safety before mother gets you.